![]() ![]() In 1967, the FDA concluded that enough evidence existed to impose controls on diazepam similar to those on amphetamines and barbiturates. But not long after Valium’s approval, it began losing some of its luster amid reports of addiction. At its peak of popularity in 1978, Americans consumed more than 2 billion of the tablets. From the late 1960s to the early 1980s, “Mother’s Little Helper” (as described by the Rolling Stones in a 1966 song) was the Western world’s most widely prescribed drug. Valium went on to become the pharmaceutical industry’s first $100 million brand, and, according to Andrea Tone, author of The Age of Anxiety: A History of America’s Turbulent Affair with Tranquilizers, diazepam “rapidly became a staple in medicine cabinets, as common as toothbrushes and razors.”Īpproved by the Food and Drug Administration in 1963, Valium has now been with us for half a century. Diazepam-which the company’s advertising team dubbed Valium, after the Latin valere (for “to be healthful”)-was more potent than Librium and lacked its unpleasant aftertaste. The first of these, Librium, was followed by an even better “benzo” that Sternbach and his team synthesized in 1959. But that research would propel him to become one of the company’s top scientists, and in the mid-1950s he stumbled upon benzodiazepines, an entirely new category of tranquilizers that were capable of calming the mind without compromising mental functioning. headquarters of Hoffmann-La Roche laboratories, fleeing his Basel home in advance of the Nazis, he began with innocuous work: synthesizing vitamins. In 1941, when chemist Leo Sternbach transferred to the U.S. ![]()
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